"Oh yah Mobb Deep, You wanna fuck with us, You Little young ass mutha fuckas Don't one of you niggas got sickle-cell or something.  You fucking with me, nigga ? You fuck around and catch a seizure or a heart-attack.  You better back the fuck up Before you get smacked the fuck up."

Before Tupac went to jail he did an article in Vibe about giving up Thug Life.  When Pac was in jail he was listening to the radio and heard a song by Mobb Deep which said "Thug Life, we still livin' it".  So he had a bunch of his homies go to the Mobb Deep concert screaming Thug Life, trying to start shit, but Mobb Deep wouldn't even acknowledge them.   Mobb Deep likes to talk a lot of shit in songs, but never backs them up.   Which is why Tupac says "Next time grown folks talking niggaz close your mouth."  Tupac considered himself on an entirely higher level than Mobb Deep and talked down to them like kids.  Tupac smashed on them in the song Hit Em Up, even dissing the fact that one of them has sickel cell.  Mobb Deep retaliated with "Drop a Gem on em".